Endocrine Abstracts

Background and aims: Maternal BMI and weight gain are associated with maternal and fetal complications in gestational diabetes (GD), but their relative contribution is not clearly defined. Our aim was to determine the influence of BMI and weight gain in the evolution of GD.Material and methods: Multicenter, retrospective study of women diagnosed with GD at the medical centers of the Portuguese Group for the Study of Diabetes and Pregnancy in 2011. We use...

Introduction: The main purpose of this case is to present a case in which the left kurtosis interval of the fertile phase curve, may be evaluated by cheeking the biophysical changing pattern of reproducible methods of viscoelasticity and transparency of the cervical secretion.Case report: This case report included a 24 years old woman who plots a curve in which integrates two biomarkers in relation to the fertile window at the follicular phase. It was re...

Background: Cases of combined primary aldosteronism and preclinical Cushing’s syndrome are reported extremely rare.Highlight of a report: An unusual case of hyperaldosteronism due to bilateral macronodular adenomas with a left renal mass in a 55-year-old male is presented. MRI scan of the abdomen revealed a 4.5 cm mass of the right adrenal and two nodules in the left adrenal sized 2 and 3 cm, respectively in diameter. Additionally, a large mass on t...

The coeliac disease is the autoimmunity disease of small intestine, which is the immune response result to various proteins of cereals, especially wheat gliadin. in adulthood it often manifests with various symptomatology, which includes metabolic osteopathy arising on secondary hyperparathyreosis.There is casuistic model of 24-year-old patient with Down syndrome and documented autoimmunity thyroiditis, where the coeliac disease manifested by serious hyp...

BackgroundIt is known that the thyroid gland is sensitive to the damaging effects of irradiation, and patients who have received radiotherapy for tumor treatment require regular thyroid screening subsequently. A few cases of thyroid cancer after receiving 131I-metaiodobenzylguanidine (MIBG) therapy in the treatment of neuroblastoma in childhood have been described (HM van Santen et al 2012; SC Clement et al, 2013). Here, we report the two cases of papill...

Background: The combination of a toxic adenoma and Graves’ disease compose the Marine-Lenhart syndrome. This condition is estimated to occur in 0.8-2.7% of Graves’ disease patients and only few cases are reported in the literature.Patient findings: A 29-year-old female patient was referred to our outpatient clinic due to subclinical hyperthyroidism and a newly discovered thyroid nodule on the right thyroid lobe. She had no thyreotoxic symptoms ...

Introduction: Obesity is known to be a disease of civilization. Both genetic and environmental factors play a role in the development of obesity. In the vast majority of cases, the main factor is eating disorders and hypodynamy. The modern human exceeds daily food demand mainly due to saturated fats and refined carbohydrates, with lack of fibre and vitamin. We decided to test the source of folic acid, because this vitamin is part of the folate cycle as a coenzyme to reduce hom...

During menopause, plasma lipids change in an unfavourable way to a more atherogenic pattern with, increased total and LDL-cholesterol and decreased HDL cholesterol concentrations. Women with POI show increased cardiovascular morbidity and mortality regardless of the cause of the ovarian insufficiency. The treatment of premature ovarian failure in patients presenting extremely low HLD-C is a real challenge.We present the case of a 29 ye...

Rathke’s cleft cysts (RCCs) are benign epithelium-lined cystic remnants of the embryonic Rathke’s pouch. We report a case of a previously fit and well 30-year-old lady with an incidental finding of a cystic pituitary lesion, discovered when she took part in a clinical trial as a normal volunteer. She had no history to suggest endocrine dysfunction.Pituitary function tests showed prolactin 302 mU/l (ref <630), LH 2.2 U/l, FSH 4.9 U/l, oestra...

During menopause, plasma lipids change in an unfavourable way to a more atherogenic pattern with, increased total and LDL-cholesterol and decreased HDL cholesterol concentrations. Women with POI show increased cardiovascular morbidity and mortality regardless of the cause of the ovarian insufficiency. The treatment of premature ovarian failure in patients presenting extremely low HLD-C is a real challenge.We present the case of a 29 ye...